分離済み変異体

tm2321

Allele Nametm2321
Allele Type通常株
Sequence NameR09E10.7
Gene Nameebax-1
Worm BaseAllele Name tm2321
Gene Name ebax-1
Sequence R09E10.7
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. Y. Jin: sluggish movement, grows well.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 4554/4555-5105/5106 (551 bp deletion)
ChromosomeIV
Putative gene structurejoin(2410..2469, 2518..2984, 3036..3335, 3380..4352, 4399..5612, 5660..5887, 5934..6819, 6871..7299, 7347..7492, 7539..7683, 7731..7859, 7908..8084)
Map position4.57
Balancer
Map position of balancer
Sequence of primersExtFwd:CATGTGGTGGCATTGTCCAT,IntFwd:GAAACCATAGCCGACGCAAT,ExtRev:GGATAGATGTGCTCGGTGGT,IntRev:CGGTGGTTCGGTCCAGTATA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Donnelly BF, Yang B, Grimme AL, Vieux KF, Liu CY, Zhou L, McJunkin K.
The developmentally timed decay of an essential microRNA family is seed-sequence dependent.
Cell Rep 2022 40(6) 111154 
[ PubMed ID = 35947946 ] [ RRC reference ]

Wang Z, Hou Y, Guo X, van der Voet M, Boxem M, Dixon JE, Chisholm AD, Jin Y.
The EBAX-type Cullin-RING E3 ligase and Hsp90 guard the protein quality of the SAX-3/Robo receptor in developing neurons.
Neuron 2013 79(5) 903-16 
[ PubMed ID = 24012004 ] [ RRC reference ]