分離済み変異体

tm2309

Allele Nametm2309
BalanceNot Required
OutCrossNot Accepted
Sequence NameF32A5.5
Gene Nameaqp-1
Worm BaseAllele Name tm2309
Gene Name aqp-1
Sequence F32A5.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. C. Kenyon: short lived.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 14755/14756-15055/15056 (300 bp deletion)
ChromosomeII
Putative gene structurecomplement(join(14114..14294, 14342..14672, 14718..14855, 14929..15055, 15107..15223, 16498..16518))
Map position0.5
Balancer
Map position of balancer
Sequence of primersIntFwd:GGCTTCTTCGATGTCAGGAT,ExtFwd:GGTTGACAGTGGATCCTCAT,IntRev:CCGAGGAAGATACTTTGCCT,ExtRev:GCAGTCTGCACCCTATCAAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Cornwell AB, Zhang Y, Thondamal M, Johnson DW, Thakar J, Samuelson AV.
The C. elegans Myc-family of transcription factors coordinate a dynamic adaptive response to dietary restriction.
Geroscience 2024 46(5) 4827-4854 
[ PubMed ID = 38878153 ] [ RRC reference ]

Cornwell A, Zhang Y, Thondamal M, Johnson DW, Thakar J, Samuelson AV.
The C. elegans Myc-family of transcription factors coordinate a dynamic adaptive response to dietary restriction.
bioRxiv 2023   
[ PubMed ID = 38045350 ] [ RRC reference ]

Anyanful A, Easley KA, Benian GM, Kalman D.
Conditioning protects C. elegans from lethal effects of enteropathogenic E. coli by activating genes that regulate lifespan and innate immunity.
Cell Host Microbe 2009 5(5) 450-62 
[ PubMed ID = 19454349 ] [ RRC reference ]