分離済み変異体

tm2299

Allele Nametm2299
BalanceCompleted
OutCrossNot Accepted
Sequence NameC07G1.4
Gene Namewsp-1
Worm BaseAllele Name tm2299 (x1)
Gene Name wsp-1
Sequence C07G1.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 21155/21156-21336/21337 (181 bp deletion)
ChromosomeIV
Putative gene structurecomplement(join(19388..19478, 19575..19741, 19797..19919, 19965..20228, 20277..20472, 20926..21195, 21244..21352, 21590..21736, 22312..23408, 27903..28018, 28496..28825))
Map position3.66
BalancernT1
Map position of balancer
Sequence of primersExtFwd:TGTATCTTCACAGGGGCGAA,ExtRev:CGGATCCACTCCAACACGAC,IntRev:ATTGGCGGAGGTCAAGGGAT,IntFwd:ACAGGGGCGAAACCCAGTAG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Shi X, Duan F, Lin L, Xu Q, Xu T, Zhang R.
WIP-1 and DBN-1 promote scission of endocytic vesicles by bridging actin and Dynamin-1 in the C. elegans intestine.
J Cell Sci 2019 132(12)  
[ PubMed ID = 31118234 ] [ RRC reference ]

Alan JK, Struckhoff EC, Lundquist EA.
Multiple cytoskeletal pathways and PI3K signaling mediate CDC-42-induced neuronal protrusion in C. elegans.
Small GTPases 2013 4(4) 208-20 
[ PubMed ID = 24149939 ] [ RRC reference ]

Mohamed AM, Boudreau JR, Yu FP, Liu J, Chin-Sang ID.
The Caenorhabditis elegans Eph receptor activates NCK and N-WASP, and inhibits Ena/VASP to regulate growth cone dynamics during axon guidance.
PLoS Genet 2012 8(2) e1002513 
[ PubMed ID = 22383893 ] [ RRC reference ]