分離済み変異体

tm2280

Allele Nametm2280
BalanceCompleted
OutCrossNot Accepted
Sequence NameM01E5.5
Gene Nametop-1
Worm BaseAllele Name tm2280 (x1)
Gene Name top-1
Sequence M01E5.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. H-S. Koo: L2-L3 lethal.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 22655/22656-22950/22951 (295 bp deletion)
ChromosomeI
Putative gene structurejoin(20598..20996, 21501..21716, 22207..23688, 23738..23980, 24759..24839)
Map position17.44
Balancer,tmC27[tmIs1239]
Map position of balancer
Sequence of primersIntFwd:CTATTCGCTCCACCATACAT,ExtFwd:CCCTTCAACACTGTGGACCA,IntRev:ATCGTCAGTATACCGCTCAC,ExtRev:AGCCGTAGCACGTTGTCGAA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]