分離済み変異体

tm2279

Allele Name

tm2279

Balance

Not Required

OutCross

Not Accepted

Sequence Name

F48D6.3

Gene Name

hlh-13

Worm Base

Allele Name

tm2279

Gene Name

hlh-13

Sequence

F48D6.3

Phenotype

homozygous viable. Dr. O. Hobert: ASE & AIY fate markers normal.

Mutation site

4762/4763-5255/5256 (493 bp deletion)

Chromosome

Putative gene structure

join(4555..4740, 4801..4907, 5687..5775, 5823..5884)

Map position

-7.86

Balancer

Map position of balancer

Sequence of primers

ExtFwd:CACTTGATCACAAGTGCGAT,ExtRev:GTGGAGTCACGCATGACATT,IntFwd:ACCCATTCGTCTCTGTCTTT,IntRev:CTGCCGTTTACGCATACACA

Distributed lab

Depositor

Dr. S. Mitani

References

Please submit your publication

Aguilar GR, Vidal B, Ji H, Evenblij J, Liao CP, Ji H, Valperga G, Fang-Yen C, Hobert O.
Functional analysis of conserved C. elegans bHLH family members uncovers lifespan control by a peptidergic hub neuron.
PLoS Biol 2025 23(1) e3002979
[ PubMed ID = 39761329 ] [ RRC reference ]

Aguilar GR, Vidal B, Ji H, Evenblij J, Ji H, Valperga G, Liao CP, Fang-Yen C, Hobert O.
Functional analysis of conserved C. elegans bHLH family members uncovers lifespan control by a peptidergic hub neuron.
bioRxiv 2024
[ PubMed ID = 39071424 ] [ RRC reference ]

Maicas M, Jimeno-Martín Á, Millán-Trejo A, Alkema MJ, Flames N.
The transcription factor LAG-1/CSL plays a Notch-independent role in controlling terminal differentiation, fate maintenance, and plasticity of serotonergic chemosensory neurons.
PLoS Biol 2021 19(7) e3001334
[ PubMed ID = 34232959 ] [ RRC reference ]

Luo S, Horvitz HR.
The CDK8 Complex and Proneural Proteins Together Drive Neurogenesis from a Mesodermal Lineage.
Curr Biol 2017 27(5) 661-672
[ PubMed ID = 28238659 ] [ RRC reference ]

Bou Dib P, Gnägi B, Daly F, Sabado V, Tas D, Glauser DA, Meister P, Nagoshi E.
A conserved role for p48 homologs in protecting dopaminergic neurons from oxidative stress.
PLoS Genet 2014 10(10) e1004718
[ PubMed ID = 25340742 ] [ RRC reference ]