分離済み変異体

tm2267

Allele Nametm2267
BalanceNot Required
OutCrossNot Accepted
Sequence NameY40G12A.2
Gene Nameubh-2
Worm BaseAllele Name tm2267
Gene Name ubh-2
Sequence Y40G12A.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. H. Inoue: normal locomotion and defecation.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 2239/2240-2468/2469 (229 bp deletion)
ChromosomeV
Putative gene structurecomplement(join(2021..2098, 2187..2317, 2368..2487, 2535..2895, 2941..3000))
Map position-0.05
Balancer
Map position of balancer
Sequence of primersExtFwd:CTAAATCCCAACGAGTGCCA,IntFwd:CCAACGAGTGCCATTGCCGA,ExtRev:CAAGTTCCGGAGTTCGCGAG,IntRev:CGCGAGTTTCGTGCAAAGCA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Nagata A, Itoh F, Sasho A, Sugita K, Suzuki R, Hinata H, Shimoda Y, Suzuki E, Maemoto Y, Inagawa T, Fujikawa Y, Ikeda E, Fujii C, Inoue H.
The evolutionarily conserved deubiquitinase UBH1/UCH-L1 augments DAF7/TGF-β signaling, inhibits dauer larva formation, and enhances lung tumorigenesis.
J Biol Chem 2020 295(27) 9105-9120 
[ PubMed ID = 32371398 ] [ RRC reference ]