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分離済み変異体

Allele Name		tm2262
Balance		Completed
OutCross		Not Accepted
Sequence Name		K04D7.1
Gene Name		rack-1
Worm Base	Allele Name	tm2262 (x1)
	Gene Name	rack-1
	Sequence	K04D7.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		Let or Ste. Dr. E. Lundquist: slow-growing, semi-sterile. Dr. H.C. Korswagen: no QL migration defect or ALM/PLM polarity defects in the F1. Dr. Y. Jin: unable to homozygous the mutants.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		8118/8119-8449/8450 (331 bp deletion)
Chromosome		IV
Putative gene structure		join(7951..8065, 8114..8297, 8341..8488, 8541..9071)
Map position		4.56
Balancer		nT1 [qIs51],hT2
Map position of balancer
Sequence of primers		IntRev:GTACAAGTGCTTGCCCTCGT,ExtFwd:AGCTTACCGGAACCCTCGAG,ExtRev:GTCGTTTCCTGGAAGGGTGT,IntFwd:GGGTCACACCGGATGGGTTA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Mazzetto M, Gonzalez LE, Sanchez N, Reinke V. Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis. Genome Res 2024 34(1) 57-69  [ PubMed ID = 38164610 ] [ RRC reference ] Andrusiak MG, Sharifnia P, Lyu X, Wang Z, Dickey AM, Wu Z, Chisholm AD, Jin Y. Inhibition of Axon Regeneration by Liquid-like TIAR-2 Granules. Neuron 2019 104(2) 290-304.e8  [ PubMed ID = 31378567 ] [ RRC reference ] Huang H, Zhu Y, Eliot MN, Knopik VS, McGeary JE, Carskadon MA, Hart AC. Combining Human Epigenetics and Sleep Studies in Caenorhabditis elegans: A Cross-Species Approach for Finding Conserved Genes Regulating Sleep. Sleep 2017 40(6)   [ PubMed ID = 28431118 ] [ RRC reference ] Demarco RS, Lundquist EA. RACK-1 acts with Rac GTPase signaling and UNC-115/abLIM in Caenorhabditis elegans axon pathfinding and cell migration. PLoS Genet 2010 6(11) e1001215  [ PubMed ID = 21124943 ] [ RRC reference ]