分離済み変異体

tm2260

Allele Nametm2260
BalanceNot Required
OutCrossNot Accepted
Sequence NameY47H9C.6
Gene Namecsp-3
Worm BaseAllele Name tm2260
Gene Name csp-3
Sequence Y47H9C.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 57898/57899-58091/58092 (193 bp deletion)
ChromosomeI
Putative gene structurecomplement(join(58017..58073, 58116..58352, 58397..58522))
Map position12.87
Balancer
Map position of balancer
Sequence of primersExtFwd:GCTAGCATGACATCGTCACA,IntFwd:ATTCATCGTAGCAGCGGGAA,ExtRev:CGCCTCAAACGCCACTGGAT,IntRev:CGCCACTGGATTCTCTGGTA
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Jeong PY, Kumar A, Joshi PM, Rothman JH.
Intertwined Functions of Separase and Caspase in Cell Division and Programmed Cell Death.
Sci Rep 2020 10(1) 6159 
[ PubMed ID = 32273538 ] [ RRC reference ]

Geng X, Zhou QH, Kage-Nakadai E, Shi Y, Yan N, Mitani S, Xue D.
Caenorhabditis elegans caspase homolog CSP-2 inhibits CED-3 autoactivation and apoptosis in germ cells.
Cell Death Differ 2009 16(10) 1385-94 
[ PubMed ID = 19575016 ] [ RRC reference ]

Geng X, Shi Y, Nakagawa A, Yoshina S, Mitani S, Shi Y, Xue D.
Inhibition of CED-3 zymogen activation and apoptosis in Caenorhabditis elegans by caspase homolog CSP-3.
Nat Struct Mol Biol 2008 15(10) 1094-101 
[ PubMed ID = 18776901 ] [ RRC reference ]