分離済み変異体

tm2238

Allele Nametm2238
Allele Type通常株
Sequence NameF22F1.4
Gene Namemir-237
Worm BaseAllele Name tm2238
Gene Name mir-237
Sequence F22F1.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. L. Mathies: normal gonad and body morphology and locomotion.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 5401/5402-TG-5578/5579 (177 bp deletion + 2 bp insertion)
ChromosomeX
Putative gene structure5551..5574
Map position-0.48
Balancer
Map position of balancer
Sequence of primersIntRev:GGCCGTCGACGATTATCTAA,IntFwd:GTCTGTCTTACTGCACCTGT,ExtRev:TTACGGCCGTCGACGATTAT,ExtFwd:GTTGCGTGTTCGATCGTGTC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Wang SY, Kim K, O'Brown ZK, Levan A, Dodson AE, Kennedy SG, Chernoff C, Greer EL.
Hypoxia induces transgenerational epigenetic inheritance of small RNAs.
Cell Rep 2022 41(11) 111800 
[ PubMed ID = 36516753 ] [ RRC reference ]

Metheetrairut C, Adams BD, Nallur S, Weidhaas JB, Slack FJ.
cel-mir-237 and its homologue, hsa-miR-125b, modulate the cellular response to ionizing radiation.
Oncogene 2017 36(4) 512-524 
[ PubMed ID = 27321180 ] [ RRC reference ]