分離済み変異体

tm2235

Allele Name

tm2235

Balance

Not Required

OutCross

Not Accepted

Sequence Name

Y110A2AL.13

Gene Name

pinn-1

Worm Base

Allele Name

tm2235

Gene Name

pinn-1

Sequence

Y110A2AL.13

Phenotype

homozygous viable. Dr. K.F. O'Connell: normal hatching, locomotion and body shape.

Mutation site

52164/52165-52528/52529 (364 bp deletion)

Chromosome

Putative gene structure

complement(join(49933..50055, 50799..50905, 52115..52262, 52371..52444, 52492..52546))

Map position

-9.56

Balancer

Map position of balancer

Sequence of primers

ExtRev:ATACGGGCCAATTTTCCAGA,IntRev:GATGTCCGATAATTCGCTGC,IntFwd:CCCTCAATGTTCGACGCATC,ExtFwd:GGCGGTTACAGTACCCCAAG

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Stubbe FX, Ponsard P, Steiner FA, Hermand D.
SSUP-72/PINN-1 coordinates RNA-polymerase II 3' pausing and developmental gene expression in C. elegans.
Nat Commun 2025 16(1) 2624
[ PubMed ID = 40097442 ] [ RRC reference ]

Salzberg Y, Pechuk V, Gat A, Setty H, Sela S, Oren-Suissa M.
Synaptic Protein Degradation Controls Sexually Dimorphic Circuits through Regulation of DCC/UNC-40.
Curr Biol 2020 30(21) 4128-4141.e5
[ PubMed ID = 32857970 ] [ RRC reference ]

Chen F, Chisholm AD, Jin Y.
Tissue-specific regulation of alternative polyadenylation represses expression of a neuronal ankyrin isoform in C. elegans epidermal development.
Development 2017 144(4) 698-707
[ PubMed ID = 28087624 ] [ RRC reference ]

Chuang M, Hsiao TI, Tong A, Xu S, Chisholm AD.
DAPK interacts with Patronin and the microtubule cytoskeleton in epidermal development and wound repair.
Elife 2016 5
[ PubMed ID = 27661253 ] [ RRC reference ]

Del Rosario JS, Feldmann KG, Ahmed T, Amjad U, Ko B, An J, Mahmud T, Salama M, Mei S, Asemota D, Mano I.
Death Associated Protein Kinase (DAPK) -mediated neurodegenerative mechanisms in nematode excitotoxicity.
BMC Neurosci 2015 16 25
[ PubMed ID = 25899010 ] [ RRC reference ]