分離済み変異体

tm2218

Allele Nametm2218
BalanceNot Required
OutCrossNot Accepted
Sequence NameB0024.14
Gene Namecrm-1
Worm BaseAllele Name tm2218
Gene Name crm-1
Sequence B0024.14
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. P. Bazzicalupo: normal egg laying and fertility. Dr. A. Frand: molting defective.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 38329/38330-T-38521/38522 (192 bp deletion +1 bp insertion)
ChromosomeV
Putative gene structurejoin(complement(AL021478.1:559..628, 39737..39879, 39320..39431, 38531..38914, 38176..38461, 38017..38130, 37824..37969, 37689..37779, 37471..37640, 37079..37423, 36693..37010, 36457..36647, 36288..36409, 36150..36242, 36000..36099))
Map position2.49
Balancer
Map position of balancer
Sequence of primersExtFwd:AAGTCCATTGGCACATCTGT,IntFwd:CCTCAGAGAACACAGTTCGA,ExtRev:TGTGCACTGTCCTCCTATGT,IntRev:GTCCACCTGATAGTATCCGT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Liu Z, Shi H, Szymczak LC, Aydin T, Yun S, Constas K, Schaeffer A, Ranjan S, Kubba S, Alam E, McMahon DE, He J, Shwartz N, Tian C, Plavskin Y, Lindy A, Dad NA, Sheth S, Amin NM, Zimmerman S, Liu D, Schwarz EM, Smith H, Krause MW, Liu J.
Promotion of bone morphogenetic protein signaling by tetraspanins and glycosphingolipids.
PLoS Genet 2015 11(5) e1005221 
[ PubMed ID = 25978409 ] [ RRC reference ]

Fung WY, Fat KF, Eng CK, Lau CK.
crm-1 facilitates BMP signaling to control body size in Caenorhabditis elegans.
Dev Biol 2007 311(1) 95-105 
[ PubMed ID = 17869238 ] [ RRC reference ]