分離済み変異体

tm2211

Allele Nametm2211
BalanceCompleted
OutCrossNot Accepted
Sequence NameY48G1C.4
Gene Namepgs-1
Worm BaseAllele Name tm2211 (x1)
Gene Name pgs-1
Sequence Y48G1C.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. M. Sundaram: sterile.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 5370/5371-6013/6014 (643 bp deletion)
ChromosomeI
Putative gene structurejoin(2432..2527, 3326..3541, 4794..4921, 4977..5083, 5777..5848, 5902..6206, 6455..6871)
Map position-20.87
BalancerhT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersIntFwd:CAGCGAGCCGACGAGATTAT,ExtFwd:TTCCACACACCGGAGCTTAG,IntRev:GAACCGATCGATAACCGTAA,ExtRev:GTGCAGCCATGTCAAGTATC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
C. elegans Deletion Mutant Consortium.
large-scale screening for targeted knockouts in the Caenorhabditis elegans genome.
G3 (Bethesda) 2012 2(11) 1415-25 
[ PubMed ID = 23173093 ] [ RRC reference ]

Sakamoto T, Inoue T, Otomo Y, Yokomori N, Ohno M, Arai H, Nakagawa Y.
Deficiency of cardiolipin synthase causes abnormal mitochondrial function and morphology in germ cells of Caenorhabditis elegans.
J Biol Chem 2012 287(7) 4590-601 
[ PubMed ID = 22174409 ] [ RRC reference ]