分離済み変異体

tm2207

Allele Nametm2207
BalanceCompleted
OutCrossNot Accepted
Sequence NameZK370.3
Gene Namehipr-1
Worm BaseAllele Name tm2207 (x1)
Gene Name hipr-1
Sequence ZK370.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 2928/2929-ATATTTTC-3268/3269 (340 bp deletion + 8 bp insertion)
ChromosomeIII
Putative gene structurejoin(1842..2113, 2162..2418, 2479..3002, 3087..3198, 3280..3641, 4261..4357, 4407..4490, 4947..5736, 6121..6382, 6626..6649)
Map position-0.09
BalancerhT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersExtFwd:GGGAGGAAAGCTTTTCGCCT,IntFwd:GTCATATCTCCTCCTCACAC,ExtRev:CAGCATCACCCTCCGCCTTT,IntRev:AGCAGTAATCTCTTCGTCCT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
C. elegans Deletion Mutant Consortium.
large-scale screening for targeted knockouts in the Caenorhabditis elegans genome.
G3 (Bethesda) 2012 2(11) 1415-25 
[ PubMed ID = 23173093 ] [ RRC reference ]

Parker JA, Metzler M, Georgiou J, Mage M, Roder JC, Rose AM, Hayden MR, Néri C.
Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity.
J Neurosci 2007 27(41) 11056-64 
[ PubMed ID = 17928447 ] [ RRC reference ]