分離済み変異体

tm2188

Allele Nametm2188
Allele Typeバランス済
Sequence NameM03C11.2
Gene Namechl-1
Worm BaseAllele Name tm2188
Gene Name chl-1
Sequence M03C11.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 10729/10730-GATCCAAGGTATGTTAAAATCG-11573/11574 (844 bp deletion + 22 bp insertion)
ChromosomeIII
Putative gene structurecomplement(join(9937..10197, 10671..10892, 11050..11455, 11862..12073, 12381..12691, 13426..14005, 14799..14912, 15378..15480, 15542..15879))
Map position2.48
BalancerhT2 bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersExtFwd:CGCTGACCAAGGATTCCTGT,ExtRev:CAGGTTCCCTCTACTCTGCT,IntFwd:CCTTCATCCGTTCCCTCAAC,IntRev:TAACCCTCGCACTGCGTCTA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Chung G, O'Neil NJ, Rose AM.
CHL-1 provides an essential function affecting cell proliferation and chromosome stability in Caenorhabditis elegans.
DNA Repair (Amst) 2011 10(11) 1174-82 
[ PubMed ID = 21968058 ] [ RRC reference ]

Gilchrist EJ, O'Neil NJ, Rose AM, Zetka MC, Haughn GW.
TILLING is an effective reverse genetics technique for Caenorhabditis elegans.
BMC Genomics 2006 7 262 
[ PubMed ID = 17049087 ] [ RRC reference ]