分離済み変異体

tm2179

Allele Nametm2179
BalanceNot Required
OutCrossNot Accepted
Sequence NameY48D7A.2
Gene Nameflp-18
Worm BaseAllele Name tm2179
Gene Name flp-18
Sequence Y48D7A.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. K. Ashrai: normal fat content observed by Nile-Red staining. Dr. P. Sengupta: possible bordering phenotype, possible egl. Dr. J. Kaplan: WT aldicarb sensitivity, increased Nile red staining.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 6696/6697-7982/7983 (1286 bp deletion)
ChromosomeX
Putative gene structurecomplement(join(6181..6271, 6322..6484, 6531..6584, 6633..6782, 6832..6924, 7967..8042))
Map position-12.65
Balancer
Map position of balancer
Sequence of primersIntRev:GGGTTAGACATGCAACGGTG,ExtRev:GAGTGTCATTTGATGGGATG,IntFwd:ACTTCCGTCCGAATCGGAGA,ExtFwd:GACGAACTGTGTTTGACGTA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Cockx B, Van Bael S, Boelen R, Vandewyer E, Yang H, Le TA, Dalzell JJ, Beets I, Ludwig C, Lee J, Temmerman L.
Mass Spectrometry-Driven Discovery of Neuropeptides Mediating Nictation Behavior of Nematodes.
Mol Cell Proteomics 2023 22(2) 100479 
[ PubMed ID = 36481452 ] [ RRC reference ]

Park J, Choi W, Dar AR, Butcher RA, Kim K.
Neuropeptide Signaling Regulates Pheromone-Mediated Gene Expression of a Chemoreceptor Gene in C. elegans.
Mol Cells 2019 42(1) 28-35 
[ PubMed ID = 30453729 ] [ RRC reference ]

Stawicki TM, Takayanagi-Kiya S, Zhou K, Jin Y.
Neuropeptides function in a homeostatic manner to modulate excitation-inhibition imbalance in C. elegans.
PLoS Genet 2013 9(5) e1003472 
[ PubMed ID = 23658528 ] [ RRC reference ]