分離済み変異体

tm2175

Allele Nametm2175
BalanceNot Required
OutCrossNot Accepted
Sequence NameC07G1.3
Gene Namepct-1
Worm BaseAllele Name tm2175
Gene Name pct-1
Sequence C07G1.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. M. Han: no obvious heterochronic phenotype such as alae gaps.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 16994/16995-GAGAG-17725/17726 (731 bp deletion + 5 bp insertion)
ChromosomeIV
Putative gene structurejoin(7328..7430, 7981..8179, 8797..8900, 15844..15940, 15987..16038, 16743..16988, 17286..17417, 17509..17921, 18216..18444, 18496..18654)
Map position3.65
Balancer
Map position of balancer
Sequence of primersExtFwd:TCGGTGGCCGATTTTCGCAA,IntFwd:TTACCACGAGATGAGCCGGA,ExtRev:GACAGATTGCTCATCTCGCA,IntRev:GATCGTCCTCAAGAACGGAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Edwards SL, Morrison LM, Yorks RM, Hoover CM, Boominathan S, Miller KG.
UNC-16 (JIP3) Acts Through Synapse-Assembly Proteins to Inhibit the Active Transport of Cell Soma Organelles to Caenorhabditis elegans Motor Neuron Axons.
Genetics 2015 201(1) 117-41 
[ PubMed ID = 26354976 ] [ RRC reference ]

Ou CY, Poon VY, Maeder CI, Watanabe S, Lehrman EK, Fu AK, Park M, Fu WY, Jorgensen EM, Ip NY, Shen K.
Two cyclin-dependent kinase pathways are essential for polarized trafficking of presynaptic components.
Cell 2010 141(5) 846-58 
[ PubMed ID = 20510931 ] [ RRC reference ]