分離済み変異体

tm2150

Allele Nametm2150
BalanceNot Required
OutCrossNot Accepted
Sequence NameW03F11.6
Gene Nameafd-1
Worm BaseAllele Name tm2150
Gene Name afd-1
Sequence W03F11.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 36768/36769-37062/37063 (294 bp deletion)
ChromosomeI
Putative gene structurejoin(237..365, 3183..3455, 4184..4268, 4992..5150, 6141..6295, 12169..12335, 13919..14031, 14090..14187, 15054..15149, 25904..26083, 26796..26878, 33009..33070, 35564..36831, 37354..37449, 40175..40314, 41895..42333, 43739..44029, 45090..45473, 47485..48003, 49259..49498)
Map position-11.19
Balancer
Map position of balancer
Sequence of primersExtFwd:GATACATGGTGCACAGGGCT,IntFwd:TCTCGAGTCGAGACTACCCA,IntRev:ATCGTATCCGACACGGCACT,ExtRev:CGCAGTGTCACCTTCGATAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Cebul ER, Marivin A, Wexler LR, Perrat PN, Bénard CY, Garcia-Marcos M, Heiman MG.
Glial adherens junction proteins act with SAX-7/L1CAM to promote dendrite extension in C. elegans.
Development 2026 153(1)  
[ PubMed ID = 41312807 ] [ RRC reference ]

Cebul ER, Marivin A, Wexler LR, Perrat PN, Bénard CY, Garcia-Marcos M, Heiman MG.
SAX-7/L1CAM acts with the adherens junction proteins MAGI-1, HMR-1/Cadherin, and AFD-1/Afadin to promote glial-mediated dendrite extension.
bioRxiv 2024   
[ PubMed ID = 38260503 ] [ RRC reference ]