分離済み変異体

tm2123

Allele Nametm2123
BalanceRequest Available
OutCrossNot Accepted
Sequence NameY80D3A.3
Gene Nameceh-51
Worm BaseAllele Name tm2123
Gene Name ceh-51
Sequence Y80D3A.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. M. Maduro: Development 136, 2735 (2009).
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 18370/18371-TNCCGGTTCTAGTA-19980/19981 (1610 bp deletion + 14 bp insertion)
ChromosomeV
Putative gene structurejoin(18453..18706, 19777..20227)
Map position18.26
Balancer
Map position of balancer
Sequence of primersExtRev:GATCTGCTCGGGCGAAAGTC,IntFwd:GCACTATATGCCTAGATTCG,IntRev:CCGTCGCTCGTCAACCTTTA,ExtFwd:AGGGAGCACTATATGCCTAG
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Rasmussen JP, Feldman JL, Reddy SS, Priess JR.
Cell interactions and patterned intercalations shape and link epithelial tubes in C. elegans.
PLoS Genet 2013 9(9) e1003772 
[ PubMed ID = 24039608 ] [ RRC reference ]

Harrell JR, Goldstein B.
Internalization of multiple cells during C. elegans gastrulation depends on common cytoskeletal mechanisms but different cell polarity and cell fate regulators.
Dev Biol 2011 350(1) 1-12 
[ PubMed ID = 20875815 ] [ RRC reference ]

Owraghi M, Broitman-Maduro G, Luu T, Roberson H, Maduro MF.
Roles of the Wnt effector POP-1/TCF in the C. elegans endomesoderm specification gene network.
Dev Biol 2010 340(2) 209-21 
[ PubMed ID = 19818340 ] [ RRC reference ]

Broitman-Maduro G, Owraghi M, Hung WW, Kuntz S, Sternberg PW, Maduro MF.
The NK-2 class homeodomain factor CEH-51 and the T-box factor TBX-35 have overlapping function in C. elegans mesoderm development.
Development 2009 136(16) 2735-46 
[ PubMed ID = 19605496 ] [ RRC reference ]