Home > 分離済み変異体 > tm2105

分離済み変異体

Allele Name		tm2105
Allele Type		通常株
Sequence Name		F35B12.7
Gene Name		nlp-24
Worm Base	Allele Name	tm2105
	Gene Name	nlp-24
	Sequence	F35B12.7
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. C. Bargmann: viable, fertile, less exploratory on food. Dr. J. Alcedo: normal fertility and lifespan.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		17141/17142-17946/17947 (805 bp deletion)
Chromosome		V
Putative gene structure		join(17766..17973, 18050..18084)
Map position		3.22
Balancer
Map position of balancer
Sequence of primers		IntRev:TAACCGAGAAGAGCTCCAAC,ExtRev:GGTACGTCACGCTCGTTCAT,IntFwd:GGTATGAGTAACCGGTCTTC,ExtFwd:TGACCTTCCCAGTGTGGAGA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Liu J, Zhang P, Zheng Z, Afridi MI, Zhang S, Wan Z, Zhang X, Stingelin L, Wang Y, Tu H. GABAergic signaling between enteric neurons and intestinal smooth muscle promotes innate immunity and gut defense in Caenorhabditis elegans. Immunity 2023 56(7) 1515-1532.e9  [ PubMed ID = 37437538 ] [ RRC reference ] Park JY, Cheong MC, Cho JY, Koo HS, Paik YK. A novel functional cross-interaction between opioid and pheromone signaling may be involved in stress avoidance in Caenorhabditis elegans. Sci Rep 2020 10(1) 7524  [ PubMed ID = 32371913 ] [ RRC reference ] Harris G, Wu T, Linfield G, Choi MK, Liu H, Zhang Y. Molecular and cellular modulators for multisensory integration in C. elegans. PLoS Genet 2019 15(3) e1007706  [ PubMed ID = 30849079 ] [ RRC reference ] Mills H, Ortega A, Law W, Hapiak V, Summers P, Clark T, Komuniecki R. Opiates Modulate Noxious Chemical Nociception through a Complex Monoaminergic/Peptidergic Cascade. J Neurosci 2016 36(20) 5498-508  [ PubMed ID = 27194330 ] [ RRC reference ] Hapiak V, Summers P, Ortega A, Law WJ, Stein A, Komuniecki R. Neuropeptides amplify and focus the monoaminergic inhibition of nociception in Caenorhabditis elegans. J Neurosci 2013 33(35) 14107-16  [ PubMed ID = 23986246 ] [ RRC reference ] Cheong MC, Artyukhin AB, You YJ, Avery L. An opioid-like system regulating feeding behavior in C. elegans. Elife 2015 4   [ PubMed ID = 25898004 ] [ RRC reference ]