分離済み変異体

tm2095

Allele Name

tm2095

Balance

Not Required

OutCross

Not Accepted

Sequence Name

K09A9.2

Gene Name

rab-14

Worm Base

Allele Name

tm2095

Gene Name

rab-14

Sequence

K09A9.2

Phenotype

homozygous viable. Dr. O. Blacque: dye-filling normal. Dr. S. Eimer: normal levamisole receptor trafficking.

Mutation site

28564/28565-29266/29267 (702 bp deletion)

Chromosome

Putative gene structure

complement(join(27534..27696, 27760..27878, 28371..28615, 28762..28867))

Map position

22.93

Balancer

Map position of balancer

Sequence of primers

IntRev:ACGTGCGCATTCACTCGTCA,ExtRev:GGCTCAACACCAATGACAGA,IntFwd:GCTGCACGTGGCAAGTTCTG,ExtFwd:ATGGGTGACAAGCTCTCACA

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Yoshida K, Suehiro Y, Dejima K, Yoshina S, Mitani S.
Distinct pathways for export of silencing RNA in Caenorhabditis elegans systemic RNAi.
iScience 2023 26(10) 108067
[ PubMed ID = 37854694 ] [ RRC reference ]

Yin J, Huang Y, Guo P, Hu S, Yoshina S, Xuan N, Gan Q, Mitani S, Yang C, Wang X.
GOP-1 promotes apoptotic cell degradation by activating the small GTPase Rab2 in C. elegans.
J Cell Biol 2017 216(6) 1775-1794
[ PubMed ID = 28424218 ] [ RRC reference ]

Huang J, Wang H, Chen Y, Wang X, Zhang H.
Residual body removal during spermatogenesis in C. elegans requires genes that mediate cell corpse clearance.
Development 2012 139(24) 4613-22
[ PubMed ID = 23172915 ] [ RRC reference ]

Sasidharan N, Sumakovic M, Hannemann M, Hegermann J, Liewald JF, Olendrowitz C, Koenig S, Grant BD, Rizzoli SO, Gottschalk A, Eimer S.
RAB-5 and RAB-10 cooperate to regulate neuropeptide release in Caenorhabditis elegans.
Proc Natl Acad Sci U S A 2012 109(46) 18944-9
[ PubMed ID = 23100538 ] [ RRC reference ]

Guo P, Hu T, Zhang J, Jiang S, Wang X.
Sequential action of Caenorhabditis elegans Rab GTPases regulates phagolysosome formation during apoptotic cell degradation.
Proc Natl Acad Sci U S A 2010 107(42) 18016-21
[ PubMed ID = 20921409 ] [ RRC reference ]