分離済み変異体

tm2081

Allele Nametm2081
BalanceNot Required
OutCrossNot Accepted
Sequence NameW04G5.2
Gene Namerab-11.2
Worm BaseAllele Name tm2081
Gene Name rab-11.2
Sequence W04G5.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. O. Blacque: dye-filling normal. Dr. S. Eimer: does not affect levamisole receptor trafficking.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 3838/3839-4485/4486 (647 bp deletion)
ChromosomeI
Putative gene structurecomplement(join(3730..3887, 3938..4223, 4266..4460))
Map position9.37
Balancer
Map position of balancer
Sequence of primersExtRev:GGTGACCGGACAGAATAAAG,IntRev:ACGGTCTTCCGGGAGTTCAT,ExtFwd:GAGTTGAGGACAGGAGTTTG,IntFwd:ATGCCAATGCGTGTCTGACA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Eichel K, Uenaka T, Belapurkar V, Lu R, Cheng S, Pak JS, Taylor CA, Südhof TC, Malenka R, Wernig M, Özkan E, Perrais D, Shen K.
Endocytosis in the axon initial segment maintains neuronal polarity.
Nature 2022 609(7925) 128-135 
[ PubMed ID = 35978188 ] [ RRC reference ]

Zheng C, Diaz-Cuadros M, Chalfie M.
Hox Genes Promote Neuronal Subtype Diversification through Posterior Induction in Caenorhabditis elegans.
Neuron 2015 88(3) 514-27 
[ PubMed ID = 26539892 ] [ RRC reference ]

Sasidharan N, Sumakovic M, Hannemann M, Hegermann J, Liewald JF, Olendrowitz C, Koenig S, Grant BD, Rizzoli SO, Gottschalk A, Eimer S.
RAB-5 and RAB-10 cooperate to regulate neuropeptide release in Caenorhabditis elegans.
Proc Natl Acad Sci U S A 2012 109(46) 18944-9 
[ PubMed ID = 23100538 ] [ RRC reference ]