分離済み変異体

tm2051

Allele Name

tm2051

Allele Type

通常株

Sequence Name

F41G3.12

Gene Name

agr-1

Worm Base

Allele Name

tm2051

Gene Name

agr-1

Sequence

F41G3.12

Phenotype

homozygous viable. Dr. Y-C. Wu: no hyperactive no locomotion defect.

Mutation site

22164/22165-22587/22588 (423 bp deletion)

Chromosome

Putative gene structure

complement(join(20958..21219, 21763..21943, 22271..22329, 22449..22515, 27393..27667, 27717..27834, 27880..28008, 28055..28256, 28307..28363, 28939..29031, 29082..29173, 29224..29329, 29372..29437, 29730..29961, 30025..30172, 30218..30402, 30442..30640, 30786..30894, 30944..31062, 31198..31425, 31473..31685, 31732..31822, 31872..32082, 32129..32258, 32314..32556, 34249..34458, 34513..34567, 34614..34706, 34750..34842, 34889..35074))

Map position

0.09

Balancer

Map position of balancer

Sequence of primers

ExtFwd:CACGTCTCCTGGTGAAGCGA,IntFwd:TGGTGAAGCGACGACGTGAA,ExtRev:GCTGTGAGACTAACTTGGGA,IntRev:AGCTCTTCTCTGCCTCCCAT

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Attreed M, Desbois M, van Kuppevelt TH, Bülow HE.
Direct visualization of specifically modified extracellular glycans in living animals.
Nat Methods 2012 9(5) 477-9
[ PubMed ID = 22466794 ] [ RRC reference ]

Dejima K, Kang S, Mitani S, Cosman PC, Chisholm AD.
Syndecan defines precise spindle orientation by modulating Wnt signaling in C. elegans.
Development 2014 141(22) 4354-65
[ PubMed ID = 25344071 ] [ RRC reference ]

Blanchette CR, Perrat PN, Thackeray A, Bénard CY.
Glypican Is a Modulator of Netrin-Mediated Axon Guidance.
PLoS Biol 2015 13(7) e1002183
[ PubMed ID = 26148345 ] [ RRC reference ]

Hrus A, Lau G, Hutter H, Schenk S, Ferralli J, Brown-Luedi M, Chiquet-Ehrismann R, Canevascini S.
C. elegans agrin is expressed in pharynx, IL1 neurons and distal tip cells and does not genetically interact with genes involved in synaptogenesis or muscle function.
PLoS One 2007 2(8) e731
[ PubMed ID = 17710131 ] [ RRC reference ]