Home > 分離済み変異体 > tm2044

分離済み変異体

Allele Name		tm2044
Balance		Not Required
OutCross		Not Accepted
Sequence Name		T14F9.5
Gene Name		lin-32
Worm Base	Allele Name	tm2044
	Gene Name	lin-32
	Sequence	T14F9.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. D. Portman: strong ray-missing phenotype. Dr. O. Hobert: Nat. Meth.5, 869 (2008).
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		24537/24538-TCTTAC-25636/25637 (1099 bp deletion + 6 bp insertion)
Chromosome		X
Putative gene structure		complement(join(24191..24337, 24722..24860, 24926..25068))
Map position		-16.75
Balancer
Map position of balancer
Sequence of primers		IntRev:CGCGAGCATTCCTACTATTG,ExtFwd:TGTGTCGCCCGTTATCTTGA,IntFwd:TCTACCTACCGTAGACCCAG,ExtRev:TAGCCAATGCGCGAGCATTC
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Hori S, Mitani S. An atonal homolog, lin-32, regulates hypodermal morphogenesis in Caenorhabditis elegans. MicroPubl Biol 2023 2023   [ PubMed ID = 36873297 ] [ RRC reference ] Hori S, Mitani S. The transcription factor unc-130/FOXD3/4 contributes to the biphasic calcium response required to optimize avoidance behavior. Sci Rep 2022 12(1) 1907  [ PubMed ID = 35115609 ] [ RRC reference ] Zhang A, Noma K, Yan D. Regulation of Gliogenesis by lin-32/Atoh1 in Caenorhabditis elegans. G3 (Bethesda) 2020 10(9) 3271-3278  [ PubMed ID = 32665354 ] [ RRC reference ] Hori S, Oda S, Suehiro Y, Iino Y, Mitani S. OFF-responses of interneurons optimize avoidance behaviors depending on stimulus strength via electrical synapses. PLoS Genet 2018 14(6) e1007477  [ PubMed ID = 29939997 ] [ RRC reference ] Miller RM, Portman DS. The Wnt/beta-catenin asymmetry pathway patterns the atonal ortholog lin-32 to diversify cell fate in a Caenorhabditis elegans sensory lineage. J Neurosci 2011 31(37) 13281-91  [ PubMed ID = 21917811 ] [ RRC reference ] Doitsidou M, Flames N, Lee AC, Boyanov A, Hobert O. Automated screening for mutants affecting dopaminergic-neuron specification in C. elegans. Nat Methods 2008 5(10) 869-72  [ PubMed ID = 18758453 ] [ RRC reference ]