分離済み変異体

tm2037

Allele Nametm2037
Allele Type通常株
Sequence NameF36F2.4
Gene Namesyn-13
Worm BaseAllele Name tm2037
Gene Name syn-13
Sequence F36F2.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. S. Eimer: normal levamisole receptor trafficking.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 3350/3351-TTCTCCAATGGCAGTTTTATCTTCGGAAACGGCATCGTTTGTGTATGATGCCTGATGAGGGACAAGAGCTTGAAGAATCTGAAGATGAAGCTGATATTCGACAAAAGGACACAGAGGATGAAGATGATGAGAGTGATGA-4864/4865 (1514 bp deletion + 139 bp insertion)
ChromosomeI
Putative gene structurecomplement(join(2144..2269, 2425..2520, 2664..2954, 3637..3714, 3762..3841, 3898..3997, 4506..4562))
Map position3.4
Balancer
Map position of balancer
Sequence of primersExtFwd:CCTTCAAAGACATCTCTCCC,IntFwd:CCGATACTACTTGAATAGGC,ExtRev:ATTCCTGCTTGGGAGATCAA ,IntRev:GAAAGGCCACGCACCAGCTA
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
C. elegans Deletion Mutant Consortium.
large-scale screening for targeted knockouts in the Caenorhabditis elegans genome.
G3 (Bethesda) 2012 2(11) 1415-25 
[ PubMed ID = 23173093 ] [ RRC reference ]

Hermann GJ, Scavarda E, Weis AM, Saxton DS, Thomas LL, Salesky R, Somhegyi H, Curtin TP, Barrett A, Foster OK, Vine A, Erlich K, Kwan E, Rabbitts BM, Warren K.
C. elegans BLOC-1 functions in trafficking to lysosome-related gut granules.
PLoS One 2012 7(8) e43043 
[ PubMed ID = 22916203 ] [ RRC reference ]

Gengyo-Ando K, Kuroyanagi H, Kobayashi T, Murate M, Fujimoto K, Okabe S, Mitani S.
The SM protein VPS-45 is required for RAB-5-dependent endocytic transport in Caenorhabditis elegans.
EMBO Rep 2007 8(2) 152-7 
[ PubMed ID = 17235359 ] [ RRC reference ]