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分離済み変異体

Allele Name		tm2036
Balance		Completed
OutCross		Not Accepted
Sequence Name		Y42H9AR.3
Gene Name		rabs-5
Worm Base	Allele Name	tm2036 (x1)
	Gene Name	rabs-5
	Sequence	Y42H9AR.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile. Dr. S. Mitani: EMBO Reports 8, 152 (2007).
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		5906/5907-G-6990/6991 (1084 bp deletion + 1 bp insertion)
Chromosome		IV
Putative gene structure		complement(join(4104..4293, 4787..5209, 5260..5674, 5764..5925, 6299..6545, 6591..6788, 7165..7221))
Map position		3.6
Balancer		,nT1 [qIs51]
Map position of balancer
Sequence of primers		ExtRev:ATGACGGTCCTGCTCTATTG,IntRev:CTATTGCGATTGAGATGCTC,ExtFwd:ATGGGTGTCCCCGAGAGGAT,IntFwd:ACAGTGATGACGTCGTCTAG
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Maekawa M, Terasaka S, Mochizuki Y, Kawai K, Ikeda Y, Araki N, Skolnik EY, Taguchi T, Arai H. Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis. Proc Natl Acad Sci U S A 2014 111(11) E978-87  [ PubMed ID = 24591580 ] [ RRC reference ] C. elegans Deletion Mutant Consortium. large-scale screening for targeted knockouts in the Caenorhabditis elegans genome. G3 (Bethesda) 2012 2(11) 1415-25  [ PubMed ID = 23173093 ] [ RRC reference ] Gengyo-Ando K, Kuroyanagi H, Kobayashi T, Murate M, Fujimoto K, Okabe S, Mitani S. The SM protein VPS-45 is required for RAB-5-dependent endocytic transport in Caenorhabditis elegans. EMBO Rep 2007 8(2) 152-7  [ PubMed ID = 17235359 ] [ RRC reference ]