分離済み変異体

tm2027

Allele Nametm2027
BalanceNot Required
OutCrossNot Accepted
Sequence NameY43E12A.1
Gene Namecyb-2.1
Worm BaseAllele Name tm2027
Gene Name cyb-2.1
Sequence Y43E12A.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. J. Kimble: homozygotes are viable and fertile. Dr. H. Sawa: non Psa. Dr. A. Hajnal: normal vulval development.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 5513/5514-6149/6150 (636 bp deletion)
ChromosomeIV
Putative gene structurejoin(5856..6193, 6282..6668, 6713..6815, 6858..6983)
Map position4.78
Balancer
Map position of balancer
Sequence of primersIntFwd:ACTGCCAGAGTCACTATGTT,ExtFwd:TCGTTACCCCCCTTACAGAT,IntRev:ACTTGAGCGAGCAGAGCGAT,ExtRev:ACTCTAATGGCGCAAAGCTT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Lara-Gonzalez P, Moyle MW, Budrewicz J, Mendoza-Lopez J, Oegema K, Desai A.
The G2-to-M Transition Is Ensured by a Dual Mechanism that Protects Cyclin B from Degradation by Cdc20-Activated APC/C.
Dev Cell 2019 51(3) 313-325.e10 
[ PubMed ID = 31588029 ] [ RRC reference ]

Macaisne N, Kessler Z, Yanowitz JL.
Meiotic Double-Strand Break Proteins Influence Repair Pathway Utilization.
Genetics 2018 210(3) 843-856 
[ PubMed ID = 30242011 ] [ RRC reference ]