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分離済み変異体

Allele Name		tm1998
Balance		Completed
OutCross		Not Accepted
Sequence Name		E01F3.1
Gene Name		pde-3
Worm Base	Allele Name	tm1998 (x1)
	Gene Name	pde-3
	Sequence	E01F3.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile. Dr. P. Sengupta: lethal.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		13126/13127-14085/14086 (959 bp deletion)
Chromosome		II
Putative gene structure		join(Z82279.2:37949..38110, 8859..8959, 13433..13679, 13742..13853, 14030..14286, 14644..14762, 14830..14890, AL132949.2:101..397, AL132949.2:478..613, AL132949.2:1203..1303, AL132949.2:1462..1464)
Map position		23.75
Balancer		mnC1 [dpy-10(e128) unc52(e444) nIs190 let-?]
Map position of balancer
Sequence of primers		ExtRev:AGGTCTGTGGCCAGGATGTA,IntRev:GATGTATTCCAGCACGAGGT,ExtFwd:CTCCCGTGTCCAGCTTAAGT,IntFwd:CCTAAGCATAAGCCAAGGAT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Wang D, O'Halloran D, Goodman MB. GCY-8, PDE-2, and NCS-1 are critical elements of the cGMP-dependent thermotransduction cascade in the AFD neurons responsible for C. elegans thermotaxis. J Gen Physiol 2013 142(4) 437-49  [ PubMed ID = 24081984 ] [ RRC reference ]