分離済み変異体

tm1984

Allele Nametm1984
BalanceNot Required
OutCrossNot Accepted
Sequence NameB0041.6
Gene Nameptps-1
Worm BaseAllele Name tm1984
Gene Name ptps-1
Sequence B0041.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. C. Loer: the same phenotype as cat-4; serotonin deficient and alkaline bleach hypersensitive.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 8846/8847-10448/10449 (1602 bp deletion)
ChromosomeI
Putative gene structurecomplement(join(9049..9186, 9433..9564, 9617..9769))
Map position-1.03
Balancer
Map position of balancer
Sequence of primersIntRev:ATAGGGAGGTTGCCGCCGAT,ExtRev:GACGGAGATCGTGTATCAAC,IntFwd:TGTGTGTGGAAGGTGCGTAT,ExtFwd:GGAGTACACGGATGTGCACT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Hernandez-Lima MA, Seo B, Urban ND, Truttmann MC.
Modulation of C. elegans behavior, fitness, and lifespan by AWB/ASH-dependent death perception.
Curr Biol 2025 35(9) 2128-2138.e6 
[ PubMed ID = 40250434 ] [ RRC reference ]

Hernandez-Lima MA, Seo B, Urban ND, Truttmann MC.
C. elegans behavior, fitness, and lifespan, are modulated by AWB/ASH-dependent death perception.
bioRxiv 2024   
[ PubMed ID = 39416137 ] [ RRC reference ]

Loer CM, Calvo AC, Watschinger K, Werner-Felmayer G, O'Rourke D, Stroud D, Tong A, Gotenstein JR, Chisholm AD, Hodgkin J, Werner ER, Martinez A.
Cuticle integrity and biogenic amine synthesis in Caenorhabditis elegans require the cofactor tetrahydrobiopterin (BH4).
Genetics 2015 200(1) 237-53 
[ PubMed ID = 25808955 ] [ RRC reference ]