分離済み変異体

tm1969

Allele Nametm1969
BalanceNot Required
OutCrossNot Accepted
Sequence NameH31G24.4
Gene Namecyb-2.2
Worm BaseAllele Name tm1969
Gene Name cyb-2.2
Sequence H31G24.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. J. Kimble: homozygotes are viable and fertile. Dr. K. Subramaniam: normal locomotion.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 2098/2099-GAGGGAGAGAAAAAT-2520/2521 (422 bp deletion + 15 bp insertion)
ChromosomeI
Putative gene structurejoin(2383..2786, 2877..3263, 3308..3410, 3453..3578)
Map position-1.72
Balancer
Map position of balancer
Sequence of primersExtRev:CTGGACTGGTACTTTTCCTG,IntRev:ACCCTAATGGCGCAAAGCTT,ExtFwd:GGCCTGACATTCCAACTATA,IntFwd:TACCATGGAAAGAACGCCAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Lara-Gonzalez P, Moyle MW, Budrewicz J, Mendoza-Lopez J, Oegema K, Desai A.
The G2-to-M Transition Is Ensured by a Dual Mechanism that Protects Cyclin B from Degradation by Cdc20-Activated APC/C.
Dev Cell 2019 51(3) 313-325.e10 
[ PubMed ID = 31588029 ] [ RRC reference ]