分離済み変異体

tm1950

Allele Nametm1950
Allele Type通常株
Sequence NameC02F4.1
Gene Nameced-5
Worm BaseAllele Name tm1950
Gene Name ced-5
Sequence C02F4.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) [F01D4] 33445/33446-[F01D4] 33965/33966 (520 bp deletion)
ChromosomeIV
Putative gene structurejoin(32257..32302, 32346..32702, 32752..32945, 32993..33129, 33177..33394, 33623..34711, 35028..35106, 35155..35286, 35449..35734, 35831..35992, 36039..36355, 37181..37256, 37616..37772, 37820..[C02F4]488, 1143..1274, 1322..1534, 1579..1923, 1972..2711, 2766..3319)
Map position4.61
Balancer
Map position of balancer
Sequence of primersIntRev:CACGCCATCTCAACACATTC,ExtFwd:GTTTACGGGCAGCACGGAGA,IntFwd:CGTATCGACAAGTGACGGAT,ExtRev:TCCGAAGTCTCACGATCATG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Harders RH, Morthorst TH, Lande AD, Hesselager MO, Mandrup OA, Bendixen E, Stensballe A, Olsen A.
Dynein links engulfment and execution of apoptosis via CED-4/Apaf1 in C. elegans.
Cell Death Dis 2018 9(10) 1012 
[ PubMed ID = 30262881 ] [ RRC reference ]

Stavoe AK, Colón-Ramos DA.
Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton.
J Cell Biol 2012 197(1) 75-88 
[ PubMed ID = 22451697 ] [ RRC reference ]

Nelson JC, Colón-Ramos DA.
Serotonergic neurosecretory synapse targeting is controlled by netrin-releasing guidepost neurons in Caenorhabditis elegans.
J Neurosci 2013 33(4) 1366-76 
[ PubMed ID = 23345213 ] [ RRC reference ]

Morthorst TH, Olsen A.
Cell-nonautonomous inhibition of radiation-induced apoptosis by dynein light chain 1 in Caenorhabditis elegans.
Cell Death Dis 2013 4(9) e799 
[ PubMed ID = 24030151 ] [ RRC reference ]