Home > 分離済み変異体 > tm1947

分離済み変異体

Allele Name		tm1947
Balance		Not Required
OutCross		Not Accepted
Sequence Name		ZK84.7
Gene Name		ins-20
Worm Base	Allele Name	tm1947
	Gene Name	ins-20
	Sequence	ZK84.7
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. C. Kenyon: grossly normal morphology and fertility, does not form dauer at 25C. Dr. P. Roy: does not delete CDS. Dr. Q.L. Ch'ng: normal locomotion and egg-laying. Dr. P.W. Sternberg: normal locomotion.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		13831/13832-14308/14309 (477 bp deletion)
Chromosome		II
Putative gene structure		join(14456..14624, 14674..14747)
Map position		-0.63
Balancer
Map position of balancer
Sequence of primers		IntFwd:ACTCTTCCAGCAGACTAGAT,ExtFwd:GCAGCAATGATCTCTCCTAG,IntRev:TGAGGGTTAATCGCAAGACA,ExtRev:CACCGCCAATGGTCTCTGGT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Le TA, Temmerman L, Roy C. Nictation behavior in nematodes. BMC Biol 2025 23(1) 356  [ PubMed ID = 41350688 ] [ RRC reference ] Takeuchi S, Ali MS, Tanimoto Y, Kage-Nakadai E. Lactococcus kimchii extends lifespan and alleviates motility decline in Caenorhabditis elegans through ins-20, an insulin-like peptide gene. Biosci Microbiota Food Health 2024 43(3) 267-274  [ PubMed ID = 38966057 ] [ RRC reference ] Fernandes de Abreu DA, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F, Cornils A, Regenass M, Neagu A, Ostojic I, Liu C, Cho Y, Sifoglu D, Shen Y, Fontana W, Lu H, Csikasz-Nagy A, Murphy CT, Antebi A, Blanc E, Apfeld J, Zhang Y, Alcedo J, Ch'ng Q. An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology. PLoS Genet 2014 10(3) e1004225  [ PubMed ID = 24675767 ] [ RRC reference ] Hung WL, Hwang C, Gao S, Liao EH, Chitturi J, Wang Y, Li H, Stigloher C, Bessereau JL, Zhen M. Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development. EMBO J 2013 32(12) 1745-60  [ PubMed ID = 23665919 ] [ RRC reference ]