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分離済み変異体

Allele Name		tm1922
Balance		Not Required
OutCross		Not Accepted
Sequence Name		ZC334.10
Gene Name		ins-29
Worm Base	Allele Name	tm1922
	Gene Name	ins-29
	Sequence	ZC334.10
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. C. Kenyon: grossly normal morphology and fertility, does not form dauer at 25C. Dr. P. Roy: normal muscle arm development. Dr. K. Ashrafi: slightly increased Nile Red staining. Dr. M. Driscoll: normal dauer formation. Dr. Q.L. Ch'ng: normal locomotion, egg-laying and body shape. Dr. P.W. Sternberg: normal locomotion.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		13580/13581-14412/14413 (832 bp deletion)
Chromosome		I
Putative gene structure		join(13173..13323, 13952..14031)
Map position		22.57
Balancer
Map position of balancer
Sequence of primers		ExtFwd:CGGCAGAGCTACAGAAACGT,IntFwd:AGCCTTTGAAAGCGGAGCTA,ExtRev:AGCTGGGTCTTTCTGCATCT,IntRev:GTGCCGGCAGCCAAAATTCA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Burton NO, Furuta T, Webster AK, Kaplan RE, Baugh LR, Arur S, Horvitz HR. Insulin-like signalling to the maternal germline controls progeny response to osmotic stress. Nat Cell Biol 2017 19(3) 252-257  [ PubMed ID = 28166192 ] [ RRC reference ] Fernandes de Abreu DA, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F, Cornils A, Regenass M, Neagu A, Ostojic I, Liu C, Cho Y, Sifoglu D, Shen Y, Fontana W, Lu H, Csikasz-Nagy A, Murphy CT, Antebi A, Blanc E, Apfeld J, Zhang Y, Alcedo J, Ch'ng Q. An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology. PLoS Genet 2014 10(3) e1004225  [ PubMed ID = 24675767 ] [ RRC reference ] Hung WL, Hwang C, Gao S, Liao EH, Chitturi J, Wang Y, Li H, Stigloher C, Bessereau JL, Zhen M. Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development. EMBO J 2013 32(12) 1745-60  [ PubMed ID = 23665919 ] [ RRC reference ]