Home > 分離済み変異体 > tm1919

分離済み変異体

Allele Name		tm1919
Balance		Not Required
OutCross		Not Accepted
Sequence Name		K02G10.7
Gene Name		aqp-8
Worm Base	Allele Name	tm1919
	Gene Name	aqp-8
	Sequence	K02G10.7
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. J-C. Martinou: not hypersensitive nor hyperresistant to anoxia. Dr. C. Kenyon: normal lifespan. Dr. D.L. Baillie: resistant to osmotic stress.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		30855/30856-TAT-31340/31341 (485 bp deletion + 3 bp insertion)
Chromosome		X
Putative gene structure		complement(join(29807..30103, 30675..30793, 31154..31412, 31461..31562))
Map position		-6.87
Balancer
Map position of balancer
Sequence of primers		ExtRev:TGTAACTTGAGCACCCCTAA,IntRev:CATACTGGAATTGCGAGTCA,ExtFwd:CCACTACTGTCACTATACTC,IntFwd:CCTTTGGCTGGTTGAATGTC
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Igual Gil C, Jarius M, von Kries JP, Rohlfing AK. Neuronal Chemosensation and Osmotic Stress Response Converge in the Regulation of aqp-8 in C. elegans. Front Physiol 2017 8 380  [ PubMed ID = 28649202 ] [ RRC reference ] Khan LA, Zhang H, Abraham N, Sun L, Fleming JT, Buechner M, Hall DH, Gobel V. Intracellular lumen extension requires ERM-1-dependent apical membrane expansion and AQP-8-mediated flux. Nat Cell Biol 2013 15(2) 143-56  [ PubMed ID = 23334498 ] [ RRC reference ] Mah AK, Armstrong KR, Chew DS, Chu JS, Tu DK, Johnsen RC, Chen N, Chamberlin HM, Baillie DL. Transcriptional regulation of AQP-8, a Caenorhabditis elegans aquaporin exclusively expressed in the excretory system, by the POU homeobox transcription factor CEH-6. J Biol Chem 2007 282(38) 28074-86  [ PubMed ID = 17660295 ] [ RRC reference ]