分離済み変異体

tm1903

Allele Nametm1903
BalanceCompleted
OutCrossNot Accepted
Sequence NameY17G7B.2
Gene Nameash-2
Worm BaseAllele Name tm1903 (x1)
Gene Name ash-2
Sequence Y17G7B.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. H.C. Korswagen: lin-22-like multiple postdeirid phenotypes.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 12283/12284-12780/12781 (497 bp deletion)
ChromosomeII
Putative gene structurejoin(11683..11753, 11836..11928, 11980..12304, 13242..13462, 14218..14331, 15865..16127, 17187..17299, 18228..18428, 18624..18714, 19438..19658)
Map position5.54
Balancer,mIn1 [e128 mIs14]
Map position of balancer
Sequence of primersExtFwd:TTCGACGGCGAGGCGATTGT,IntFwd:GTCGCGGTCGATAAGCACTC,ExtRev:CGTGGCTCACGGTTTTCCCT,IntRev:CTGCCTCGTGTAGTGGTCCT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Tuckowski AM, Beydoun S, Kitto ES, Bhat A, Howington MB, Sridhar A, Bhandari M, Chambers K, Leiser SF.
fmo-4 promotes longevity and stress resistance via ER to mitochondria calcium regulation in C. elegans.
Elife 2025 13  
[ PubMed ID = 39951337 ] [ RRC reference ]

Murari E, Meadows D, Cuda N, Mangone M.
A comprehensive analysis of 3'UTRs in Caenorhabditis elegans.
Nucleic Acids Res 2024 52(13) 7523-7538 
[ PubMed ID = 38917330 ] [ RRC reference ]

Weng Y, Murphy CT.
Male-specific behavioral and transcriptomic changes in aging C. elegans neurons.
iScience 2024 27(6) 109910 
[ PubMed ID = 38783998 ] [ RRC reference ]

Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]