分離済み変異体

tm1890

Allele Nametm1890
BalanceNot Required
OutCrossNot Accepted
Sequence NameC10F3.2
Gene Namedhs-16
Worm BaseAllele Name tm1890
Gene Name dhs-16
Sequence C10F3.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. A. Antebi: gonadal Mig on low cholesterol. Dr. C. Loer: not serotonin deficient nor alkaline bleach hypersensitive.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 23034/23035-23641/23642 (607 bp deletion)
ChromosomeV
Putative gene structurejoin(23219..23419, 23758..24328, 24415..24809)
Map position-0.47
Balancer
Map position of balancer
Sequence of primersIntFwd:TCCTAGATAGGTGGAGGGTA,ExtFwd:CAGGGCGGAGCATACCTATT,IntRev:GAATCGCAGAACGACGCTTC,ExtRev:CGATATCAAGTACGGTGGAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Ow MC, Nichitean AM, Hall SE.
Somatic aging pathways regulate reproductive plasticity in Caenorhabditis elegans.
Elife 2021 10  
[ PubMed ID = 34236316 ] [ RRC reference ]

Mahanti P, Bose N, Bethke A, Judkins JC, Wollam J, Dumas KJ, Zimmerman AM, Campbell SL, Hu PJ, Antebi A, Schroeder FC.
Comparative metabolomics reveals endogenous ligands of DAF-12, a nuclear hormone receptor, regulating C. elegans development and lifespan.
Cell Metab 2014 19(1) 73-83 
[ PubMed ID = 24411940 ] [ RRC reference ]

Wollam J, Magner DB, Magomedova L, Rass E, Shen Y, Rottiers V, Habermann B, Cummins CL, Antebi A.
A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity.
PLoS Biol 2012 10(4) e1001305 
[ PubMed ID = 22505847 ] [ RRC reference ]