Home > 分離済み変異体 > tm1885

分離済み変異体

Allele Name		tm1885
Balance		Not Required
OutCross		Not Accepted
Sequence Name		F08A10.1c
Gene Name		kcnl-2
Worm Base	Allele Name	tm1885
	Gene Name	kcnl-2
	Sequence	F08A10.1c
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. H. Sawa: non Psa.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		[T02E1] 2386/2387-[T02E1] 3348/3349 (962 bp deletion)
Chromosome		I
Putative gene structure		[T02E1] join(1934..2486, 2604..2730, 2788..2876, 2926..3071, 3167..3405, 3451..3877, 3935..4062, 4113..4182, 4227..4362, 4786..4889)
Map position		2.64
Balancer
Map position of balancer
Sequence of primers		ExtFwd:CGTGTGATAATCCTCCAATC,IntFwd:TGTTCGAACTGTCGCCCAGT,ExtRev:GCACTCCTACCTGCTTAGTA,IntRev:GCACATGCTTCTCTGCCCTT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Dimitriadi M, Kye MJ, Kalloo G, Yersak JM, Sahin M, Hart AC. The neuroprotective drug riluzole acts via small conductance Ca2+-activated K+ channels to ameliorate defects in spinal muscular atrophy models. J Neurosci 2013 33(15) 6557-62  [ PubMed ID = 23575853 ] [ RRC reference ] Chotoo CK, Silverman GA, Devor DC, Luke CJ. A small conductance calcium-activated K+ channel in C. elegans, KCNL-2, plays a role in the regulation of the rate of egg-laying. PLoS One 2013 8(9) e75869  [ PubMed ID = 24040423 ] [ RRC reference ]