分離済み変異体

tm1869

Allele Nametm1869
Allele Type通常株
Sequence NameF27D9.8
Gene Namestn-2
Worm BaseAllele Name tm1869
Gene Name stn-2
Sequence F27D9.8
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. Lihsia Chen: short with hyperactive head bending.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 28260/28261-29071/29072 (811 bp deletion)
ChromosomeX
Putative gene structurecomplement(join(26625..26750, 26801..26914, 26963..27055, 27101..27265, 27311..27376, 27430..27555, 27979..28147, 28234..28382, 28437..28500, 28930..29026, 29548..29613, 29666..29729, 29775..29908, 30345..30417, 30562..30597))
Map position-1.41
Balancer
Map position of balancer
Sequence of primersExtRev:CCTTCTCTGTTGGATGGGTT,IntRev:GGGTTATATATGCCGTCCTA,ExtFwd:AGGCAAACGTTCGGGACTAA,IntFwd:ACGGTTCGGTAATATGCTTG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Cebul ER, McLachlan IG, Heiman MG.
Dendrites with specialized glial attachments develop by retrograde extension using SAX-7 and GRDN-1.
Development 2020 147(4)  
[ PubMed ID = 31988188 ] [ RRC reference ]

Zhou S, Chen L.
Neural integrity is maintained by dystrophin in C. elegans.
J Cell Biol 2011 192(2) 349-63 
[ PubMed ID = 21242290 ] [ RRC reference ]

Zhou S, Opperman K, Wang X, Chen L.
unc-44 Ankyrin and stn-2 gamma-syntrophin regulate sax-7 L1CAM function in maintaining neuronal positioning in Caenorhabditis elegans.
Genetics 2008 180(3) 1429-43 
[ PubMed ID = 18791240 ] [ RRC reference ]