Home > 分離済み変異体 > tm1848

分離済み変異体

Allele Name		tm1848
Balance		Not Required
OutCross		Not Accepted
Sequence Name		C18B12.2
Gene Name		seb-3
Worm Base	Allele Name	tm1848
	Gene Name	seb-3
	Sequence	C18B12.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		22567/22568-23332/23333 (765 bp deletion)
Chromosome		X
Putative gene structure		join(20131..20207, 20514..20635, 22092..22210, 22258..22371, 22429..22569, 23141..23443, 23492..23577, 23911..24037, 24086..24180, 24229..24364, 24560..24604)
Map position		21.8
Balancer
Map position of balancer
Sequence of primers		IntRev:ATAGCCGAGCCGAGCATGTA,IntFwd:CAGATACATGGTTTCCCGGA,ExtFwd:GCCGCACTATACAAGCCCGA,ExtRev:GCGCTCCCTGGATTTCACTA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Quach KT, Hughes GA, Chalasani SH. Interdependence between SEB-3 receptor and NLP-49 peptides shifts across predator-induced defensive behavioral modes in Caenorhabditis elegans. Elife 2025 13   [ PubMed ID = 40163376 ] [ RRC reference ] Bhandari A, Seguin A, Rothenfluh A. Synaptic Mechanisms of Ethanol Tolerance and Neuroplasticity: Insights from Invertebrate Models. Int J Mol Sci 2024 25(13)   [ PubMed ID = 38999947 ] [ RRC reference ] Cockx B, Van Bael S, Boelen R, Vandewyer E, Yang H, Le TA, Dalzell JJ, Beets I, Ludwig C, Lee J, Temmerman L. Mass Spectrometry-Driven Discovery of Neuropeptides Mediating Nictation Behavior of Nematodes. Mol Cell Proteomics 2023 22(2) 100479  [ PubMed ID = 36481452 ] [ RRC reference ] Chai CM, Park H, Sternberg PW. Brain-wide bidirectional neuropeptide modulation of individual neuron classes regulates a developmental decision. Curr Biol 2022 32(15) 3365-3373.e6  [ PubMed ID = 35679871 ] [ RRC reference ] Salim C, Kan AK, Batsaikhan E, Patterson EC, Jee C. Neuropeptidergic regulation of compulsive ethanol seeking in C. elegans. Sci Rep 2022 12(1) 1804  [ PubMed ID = 35110557 ] [ RRC reference ] Chew YL, Grundy LJ, Brown AEX, Beets I, Schafer WR. Neuropeptides encoded by nlp-49 modulate locomotion, arousal and egg-laying behaviours in Caenorhabditis elegans via the receptor SEB-3. Philos Trans R Soc Lond B Biol Sci 2018 373(1758)   [ PubMed ID = 30201834 ] [ RRC reference ] Jee C, Lee J, Lim JP, Parry D, Messing RO, McIntire SL. SEB-3, a CRF receptor-like GPCR, regulates locomotor activity states, stress responses and ethanol tolerance in Caenorhabditis elegans. Genes Brain Behav 2013 12(2) 250-62  [ PubMed ID = 22853648 ] [ RRC reference ]