分離済み変異体

tm1832

Allele Nametm1832
BalanceNot Required
OutCrossNot Accepted
Sequence NameF13B9.8
Gene Namefis-2
Worm BaseAllele Name tm1832
Gene Name fis-2
Sequence F13B9.8
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. H-S. Koo: no lethality after outcrossed several times.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 21683/21684-23100/23101 (1417 bp deletion)
ChromosomeX
Putative gene structurecomplement(join(21315..21400, 21687..21872, 22526..22658, 22719..22730))
Map position-0.19
Balancer
Map position of balancer
Sequence of primersExtFwd:CGTAACAAATCAGGCCGTAA,IntFwd:GTCCGGCAAGTGCAAGTGCT,ExtRev:GCGATCCGAAAACGATAGCT,IntRev:CATCTATGGCGCGAATGAGA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Yang X, Wei R, Meng F, Liu D, Gong X, Ruvkun G, Wei W.
Mitochondrial fission surveillance is coupled to Caenorhabditis elegans DNA and chromosome segregation integrity.
PLoS Genet 2025 21(4) e1011678 
[ PubMed ID = 40279356 ] [ RRC reference ]

Breckenridge DG, Kang BH, Kokel D, Mitani S, Staehelin LA, Xue D.
Caenorhabditis elegans drp-1 and fis-2 regulate distinct cell-death execution pathways downstream of ced-3 and independent of ced-9.
Mol Cell 2008 31(4) 586-597 
[ PubMed ID = 18722182 ] [ RRC reference ]