分離済み変異体

tm1794

Allele Nametm1794
Allele Typeバランス済
Sequence NameZK430.8
Gene Namemlt-7
Worm BaseAllele Name tm1794
Gene Name mlt-7
Sequence ZK430.8
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. A.P. Page: homozygotes are Let, but 0.5% viable Dpy. J. Biol. Chem. 284, 17549 (2009)
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 4710/4711-5234/5235 (524 bp deletion)
ChromosomeII
Putative gene structurejoin(85..139, 4958..5079, 5624..5714, 6597..6739, 7747..8106, 9084..9997, 10804..10976, 11019..11136, 11389..11587)
Map position-4.71
BalancermIn1
Map position of balancer
Sequence of primersExtFwd:CTTGAGGCCTAGGTAGGCTC,IntFwd:TAGGTAGGCTCACCCTCATG,ExtRev:GCCTGTGCAATACTGTCTTT,IntRev:TCGTTCACAGCTGGTTACTG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Dejima K, Hori S, Iwata S, Suehiro Y, Yoshina S, Motohashi T, Mitani S.
An Aneuploidy-Free and Structurally Defined Balancer Chromosome Toolkit for Caenorhabditis elegans.
Cell Rep 2018 22(1) 232-241 
[ PubMed ID = 29298424 ] [ RRC reference ]

Thein MC, Winter AD, Stepek G, McCormack G, Stapleton G, Johnstone IL, Page AP.
Combined extracellular matrix cross-linking activity of the peroxidase MLT-7 and the dual oxidase BLI-3 is critical for post-embryonic viability in Caenorhabditis elegans.
J Biol Chem 2009 284(26) 17549-63 
[ PubMed ID = 19406744 ] [ RRC reference ]