分離済み変異体

tm1781

Allele Nametm1781
BalanceNot Required
OutCrossNot Accepted
Sequence NameH14E04.1
Gene NameH14E04.1
Worm BaseAllele Name tm1781
Gene Name H14E04.1
Sequence H14E04.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 34364/34365-35101/35102 (737 bp deletion)
ChromosomeIII
Putative gene structurejoin(33264..33326, 34411..34601, 35052..35194, 35422..35499, 35942..36111, 36508..36703, 37258..37421)
Map position-14.49
Balancer
Map position of balancer
Sequence of primersExtRev:CACGCGTATTCCAGATGATG,IntRev:CTGCGGGACCCGAAAACTCA,ExtFwd:TACGCAAACACCGATTACGA,IntFwd:CGGCGCGAAAATTGGGGTTC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mahanti P, Bose N, Bethke A, Judkins JC, Wollam J, Dumas KJ, Zimmerman AM, Campbell SL, Hu PJ, Antebi A, Schroeder FC.
Comparative metabolomics reveals endogenous ligands of DAF-12, a nuclear hormone receptor, regulating C. elegans development and lifespan.
Cell Metab 2014 19(1) 73-83 
[ PubMed ID = 24411940 ] [ RRC reference ]

Martin R, Entchev EV, Kurzchalia TV, Knölker HJ.
Steroid hormones controlling the life cycle of the nematode Caenorhabditis elegans: stereoselective synthesis and biology.
Org Biomol Chem 2010 8(4) 739-50 
[ PubMed ID = 20135027 ] [ RRC reference ]

Hannich JT, Entchev EV, Mende F, Boytchev H, Martin R, Zagoriy V, Theumer G, Riezman I, Riezman H, Knölker HJ, Kurzchalia TV.
Methylation of the sterol nucleus by STRM-1 regulates dauer larva formation in Caenorhabditis elegans.
Dev Cell 2009 16(6) 833-43 
[ PubMed ID = 19531354 ] [ RRC reference ]