分離済み変異体

tm1773

Allele Nametm1773
Allele Type通常株
Sequence NameH06H21.10
Gene Nametat-2
Worm BaseAllele Name tm1773
Gene Name tat-2
Sequence H06H21.10
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. M. Han; fertile, normal growth. Dr. S. Tuck: no genetic interaction with tat-1 mutants.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 32173/32174-32800/32801 (627 bp deletion)
ChromosomeIV
Putative gene structurecomplement(join(21043..21078, 21494..21611, 21718..21815, 22337..22553, 22773..23101, 23909..24041, 24436..24829, 25605..25755, 25883..26031, 26077..26164, 27254..27397, 27604..27801, 27858..27983, 28790..29212, 30214..30282, 30419..30699, 31853..32108, 33083..33217, 33362..33460, 33510..33623, 33984..34094))
Map position1.36
Balancer
Map position of balancer
Sequence of primersExtFwd:GGACTAGGAACCACATCGTC,IntRev:AGTCGTCAACGAAATCCGCA,ExtRev:GGCTGAATCAAGTACAGCAA,IntFwd:CACATCGTCCCACGGTAGAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Nilsson L, Jonsson E, Tuck S.
Caenorhabditis elegans numb inhibits endocytic recycling by binding TAT-1 aminophospholipid translocase.
Traffic 2011 12(12) 1839-49 
[ PubMed ID = 21917090 ] [ RRC reference ]

Seamen E, Blanchette JM, Han M.
P-type ATPase TAT-2 negatively regulates monomethyl branched-chain fatty acid mediated function in post-embryonic growth and development in C. elegans.
PLoS Genet 2009 5(8) e1000589 
[ PubMed ID = 19662161 ] [ RRC reference ]

Lyssenko NN, Miteva Y, Gilroy S, Hanna-Rose W, Schlegel RA.
An unexpectedly high degree of specialization and a widespread involvement in sterol metabolism among the C. elegans putative aminophospholipid translocases.
BMC Dev Biol 2008 8 96 
[ PubMed ID = 18831765 ] [ RRC reference ]