分離済み変異体

tm1769

Allele Nametm1769
BalanceCompleted
OutCrossNot Accepted
Sequence NameM18.5
Gene Nameddb-1
Worm BaseAllele Name tm1769 (x1)
Gene Name ddb-1
Sequence M18.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. E.T. Kipreos: Mol. Cell Biol. 27, 1394 (2007).
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 20808/20809-21258/21259 (450 bp deletion)
ChromosomeIV
Putative gene structurecomplement(join(15159..15220, 15276..15381, 15433..16249, 16311..16437, 16747..16970, 17310..17644, 18256..18957, 19006..19330, 19820..20021, 20066..20354, 20814..20956, 21009..21081))
Map position5.72
BalancernT1 [qIs51]
Map position of balancer
Sequence of primersExtFwd:GCATCAACGATTCCGTGGCA,IntFwd:TACTTCTCCGAGGTTGTCGT,ExtRev:CAGTCCTTCCATGGCTTGTG,IntRev:CATGGCTTGTGGCTCCGCAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Rahman MM, Balachandran RS, Stevenson JB, Kim Y, Proenca RB, Hedgecock EM, Kipreos ET.
The Caenorhabditis elegans cullin-RING ubiquitin ligase CRL4DCAF-1 is required for proper germline nucleolus morphology and male development.
Genetics 2023 225(1)  
[ PubMed ID = 37433110 ] [ RRC reference ]

Alleva B, Clausen S, Koury E, Hefel A, Smolikove S.
CRL4 regulates recombination and synaptonemal complex aggregation in the Caenorhabditis elegans germline.
PLoS Genet 2019 15(11) e1008486 
[ PubMed ID = 31738749 ] [ RRC reference ]

Lans H, Vermeulen W.
Nucleotide Excision Repair in Caenorhabditis elegans.
Mol Biol Int 2011 2011 542795 
[ PubMed ID = 22091407 ] [ RRC reference ]

Kim Y, Kipreos ET.
The Caenorhabditis elegans replication licensing factor CDT-1 is targeted for degradation by the CUL-4/DDB-1 complex.
Mol Cell Biol 2007 27(4) 1394-406 
[ PubMed ID = 17145765 ] [ RRC reference ]