分離済み変異体

tm1765

Allele Nametm1765
BalanceNot Required
OutCrossNot Accepted
Sequence NameC38C10.1
Gene Nametkr-1
Worm BaseAllele Name tm1765
Gene Name tkr-1
Sequence C38C10.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. G. Hermann: wild-type gut granules. Dr. K. Ashrafi: no fat phenotype.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 16274/16275-17008/17009 (734 bp deletion)
ChromosomeIII
Putative gene structurejoin(15877..15899, 16023..16322, 16388..16511, 16573..16652, 16699..16846, 17267..17457, 17511..17689, 17740..17819)
Map position0.49
Balancer
Map position of balancer
Sequence of primersExtFwd:GACAGAAAGCCTACACCCAA,ExtRev:CCATCGGAAGACGTACCGGA,IntFwd:TTTTACGAATCACTGGGCTG,IntRev:GTACCGGAAGCCAATGCGGA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Hapiak V, Summers P, Ortega A, Law WJ, Stein A, Komuniecki R.
Neuropeptides amplify and focus the monoaminergic inhibition of nociception in Caenorhabditis elegans.
J Neurosci 2013 33(35) 14107-16 
[ PubMed ID = 23986246 ] [ RRC reference ]

Harris G, Mills H, Wragg R, Hapiak V, Castelletto M, Korchnak A, Komuniecki RW.
The monoaminergic modulation of sensory-mediated aversive responses in Caenorhabditis elegans requires glutamatergic/peptidergic cotransmission.
J Neurosci 2010 30(23) 7889-99 
[ PubMed ID = 20534837 ] [ RRC reference ]