分離済み変異体

tm1750

Allele Nametm1750
BalanceNot Required
OutCrossNot Accepted
Sequence NameZK256.1
Gene Namepmr-1
Worm BaseAllele Name tm1750
Gene Name pmr-1
Sequence ZK256.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) [CC4] 23461/23462-[CC4] 23714/23715 (253 bp deletion)
ChromosomeI
Putative gene structurejoin(Z81490.1:23740..24051, Z81490.1:24897..25127, Z81490.1:25190..25465, Z81490.1:26681..27254, Z81490.1:30707..31009, Z81490.1:31777..32063, 104..201, 1046..1310, 1948..2188, 2734..2852)
Map position17.16
Balancer
Map position of balancer
Sequence of primersExtFwd:GACGGCGGCAATATTCCGAG,IntFwd:CCGAGTACAAGGTAACACTA,ExtRev:CCCATGAAGGCGATGCATGT,IntRev:CAACATCGGATCCGGTGGCA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Praitis V, Simske J, Kniss S, Mandt R, Imlay L, Feddersen C, Miller MB, Mushi J, Liszewski W, Weinstein R, Chakravorty A, Ha DG, Schacht Farrell A, Sullivan-Wilson A, Stock T.
The secretory pathway calcium ATPase PMR-1/SPCA1 has essential roles in cell migration during Caenorhabditis elegans embryonic development.
PLoS Genet 2013 9(5) e1003506 
[ PubMed ID = 23696750 ] [ RRC reference ]

Kourtis N, Nikoletopoulou V, Tavernarakis N.
Small heat-shock proteins protect from heat-stroke-associated neurodegeneration.
Nature 2012 490(7419) 213-8 
[ PubMed ID = 22972192 ] [ RRC reference ]