分離済み変異体

tm1728

Allele Nametm1728
BalanceNot Required
OutCrossNot Accepted
Sequence NameC09B7.1
Gene Nameser-7
Worm BaseAllele Name tm1728
Gene Name ser-7
Sequence C09B7.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. R. Komuniecki: Genetics in press.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 42992/42993-T-43687/43688 (695 bp deletion + 1 bp insertion)
ChromosomeX
Putative gene structurejoin(36058..36389, 37087..37342, 40604..40933, 42388..42560, 43169..43306, 44163..44201, 44465..44504)
Map position-14.04
Balancer
Map position of balancer
Sequence of primersIntRev:CGCGGATTCTCTATCAATAG,ExtFwd:GGCCTGCCTTCCTGACATGT,IntFwd:ATCCTGGAGCTGGCGAGTTA,ExtRev:GACTGTAAACGCGCAGAGTC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Hapiak VM, Hobson RJ, Hughes L, Smith K, Harris G, Condon C, Komuniecki P, Komuniecki RW.
Dual excitatory and inhibitory serotonergic inputs modulate egg laying in Caenorhabditis elegans.
Genetics 2009 181(1) 153-63 
[ PubMed ID = 19001289 ] [ RRC reference ]

Chase DL, Koelle MR.
Biogenic amine neurotransmitters in C. elegans.
WormBook 2007  1-15 
[ PubMed ID = 18050501 ] [ RRC reference ]

Carre-Pierrat M, Baillie D, Johnsen R, Hyde R, Hart A, Granger L, Ségalat L.
Characterization of the Caenorhabditis elegans G protein-coupled serotonin receptors.
Invert Neurosci 2006 6(4) 189-205 
[ PubMed ID = 17082916 ] [ RRC reference ]

Hobson RJ, Hapiak VM, Xiao H, Buehrer KL, Komuniecki PR, Komuniecki RW.
SER-7, a Caenorhabditis elegans 5-HT7-like receptor, is essential for the 5-HT stimulation of pharyngeal pumping and egg laying.
Genetics 2006 172(1) 159-69 
[ PubMed ID = 16204223 ] [ RRC reference ]