分離済み変異体

tm1726

Allele Nametm1726
BalanceNot Required
OutCrossNot Accepted
Sequence NameY17G7B.2
Gene Nameash-2
Worm BaseAllele Name tm1726
Gene Name ash-2
Sequence Y17G7B.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 12371/12372-12840/12841 (469 bp deletion)
ChromosomeII
Putative gene structurejoin(11683..11753, 11836..11928, 11980..12304, 13242..13462, 14218..14331, 15865..16127, 17187..17299, 18228..18428, 18624..18714, 19438..19658)
Map position5.54
Balancer
Map position of balancer
Sequence of primersExtFwd:TTCGACGGCGAGGCGATTGT,IntFwd:GTCGCGGTCGATAAGCACTC,ExtRev:CGTGGCTCACGGTTTTCCCT,IntRev:CTGCCTCGTGTAGTGGTCCT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Huang X, Ye Q, Dai W, Zheng J, Li Y, Wang C, Luo Z, Yang J, Zhuo W, Wan QL.
Cadmium exposure induces multigenerational inheritance of germ cell apoptosis and fertility suppression in Caenorhabditis elegans.
Environ Int 2024 191 108952 
[ PubMed ID = 39159515 ] [ RRC reference ]

Wan QL, Meng X, Wang C, Dai W, Luo Z, Yin Z, Ju Z, Fu X, Yang J, Ye Q, Zhang ZH, Zhou Q.
Histone H3K4me3 modification is a transgenerational epigenetic signal for lipid metabolism in Caenorhabditis elegans.
Nat Commun 2022 13(1) 768 
[ PubMed ID = 35140229 ] [ RRC reference ]

Chow YL, Sato F.
Transgenerational lipid-reducing activity of benzylisoquinoline alkaloids in Caenorhabditis elegans.
Genes Cells 2019 24(1) 70-81 
[ PubMed ID = 30451341 ] [ RRC reference ]

Yu Y, Zhi L, Guan X, Wang D, Wang D.
FLP-4 neuropeptide and its receptor in a neuronal circuit regulate preference choice through functions of ASH-2 trithorax complex in Caenorhabditis elegans.
Sci Rep 2016 6 21485 
[ PubMed ID = 26887501 ] [ RRC reference ]