分離済み変異体

tm1700

Allele Nametm1700
BalanceNot Required
OutCrossNot Accepted
Sequence NameC32E8.4
Gene NameC32E8.4
Worm BaseAllele Name tm1700
Gene Name C32E8.4
Sequence C32E8.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. M. Driscoll: no effect on necrotic cell death.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 10931/10932-GCCACCCGAGAGTATC-11437/11438 (506 bp deletion + 16 bp insertion)
ChromosomeI
Putative gene structurejoin(10945..11112, 11164..11178)
Map position-2.6
Balancer
Map position of balancer
Sequence of primersExtFwd:GATCGATGCCATTCACCCGA,ExtRev:GATTAGCGACGGTCACGCCT,IntFwd:CCCGAGACGATGGAACTAAA,IntRev:CGTCATGAGGATCCCTATGT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Essig YJ, Leszczyszyn OI, Almutairi N, Harrison-Smith A, Blease A, Zeitoun-Ghandour S, Webb SM, Blindauer CA, Stürzenbaum SR.
Juggling cadmium detoxification and zinc homeostasis: A division of labour between the two C. elegans metallothioneins.
Chemosphere 2024 350 141021 
[ PubMed ID = 38151062 ] [ RRC reference ]

Hughes S, Stürzenbaum SR.
Single and double metallothionein knockout in the nematode C. elegans reveals cadmium dependent and independent toxic effects on life history traits.
Environ Pollut 2007 145(2) 395-400 
[ PubMed ID = 17141712 ] [ RRC reference ]