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分離済み変異体

Allele Name		tm1664
Balance		Completed
OutCross		Not Accepted
Sequence Name		ZK858.4
Gene Name		mel-26
Worm Base	Allele Name	tm1664 (x1)
	Gene Name	mel-26
	Sequence	ZK858.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile. Dr. P.E. Mains: Dev. Biol. 302, 438 (2007).
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		21822/21823-22438/22439 (616 bp deletion)
Chromosome		I
Putative gene structure		join(21853..22227, 22276..22431, 23188..23376, 23431..23748, 24195..24404, 24451..24552)
Map position		3.62
Balancer		hT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primers		ExtFwd:TTCGACGAGTGAGCGGCTGT,IntFwd:TGAGCGGCTGTTCGTCGCAT,ExtRev:TCGAGCAGCCAGAACAGCCT,IntRev:ACAGCCTTGTGAGCTCTAAT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Gomes JE, Tavernier N, Richaudeau B, Formstecher E, Boulin T, Mains PE, Dumont J, Pintard L. Microtubule severing by the katanin complex is activated by PPFR-1-dependent MEI-1 dephosphorylation. J Cell Biol 2013 202(3) 431-9  [ PubMed ID = 23918937 ] [ RRC reference ] Lu C, Mains PE. The C. elegans anaphase promoting complex and MBK-2/DYRK kinase act redundantly with CUL-3/MEL-26 ubiquitin ligase to degrade MEI-1 microtubule-severing activity after meiosis. Dev Biol 2007 302(2) 438-47  [ PubMed ID = 17069791 ] [ RRC reference ]