分離済み変異体

tm1654

Allele Nametm1654
BalanceNot Required
OutCrossNot Accepted
Sequence NameC33H5.11
Gene Nameimp-3
Worm BaseAllele Name tm1654
Gene Name imp-3
Sequence C33H5.11
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 14732/14733-15452/15453 (720 bp deletion)
ChromosomeIV
Putative gene structurecomplement(join(12578..12686, 12735..12954, 13265..13501, 13550..13653, 14121..14203, 14257..14483, 14719..14919, 15137..15239, 15510..15668, 15720..15827))
Map position3.48
Balancer
Map position of balancer
Sequence of primersIntRev:CGGTAATTTGTGAACGGGGA,ExtFwd:CGCTCCCAAGCCTGGTTAAG,IntFwd:TGGGTCCATCATCACTCCTC,ExtRev:GCAACCCTAATTCCTCCGAA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Grigorenko AP, Moliaka YK, Plotnikova OV, Smirnov A, Nikishina VA, Goltsov AY, Gusev F, Andreeva TV, Nelson O, Bezprozvanny I, Rogaev EI.
Mutational re-modeling of di-aspartyl intramembrane proteases: uncoupling physiologically-relevant activities from those associated with Alzheimer's disease.
Oncotarget 2017 8(47) 82006-82026 
[ PubMed ID = 29137240 ] [ RRC reference ]